葡萄糖酸鋅（Zinc Gluconate）：血液透析患者的潛在必要補充劑

血液透析患者存在以下一些問題：血清白蛋白水平下降、睡眠質量差和生活質量低下。由于血液透析期間血清白蛋白排泄增加，血液透析患者的血清白蛋白通常比健康個體少。此外，血液透析患者的高度炎癥和營養不良會導致血清白蛋白合成減少。在改善血清白蛋白水平上，鋅元素對白蛋白合成過程至關重要。研究表明，補充鋅可促進蛋白質合成相關酶的活性，在嚴重鋅缺乏人群中，補充葡萄糖酸鋅（Zinc Gluconate）能顯著提升白蛋白水平；同時，在糖尿病患者中，鋅元素還能減少血清白蛋白流失，這為血液透析患者提高血清白蛋白水平帶來希望。此外，鋅狀態與炎癥反應密切相關。輕度鋅缺乏會促使單核細胞生成白細胞介素 1β（IL-1β）等促炎標志物增加，而補充鋅可調節炎癥反應，降低 C 反應蛋白（CRP）等炎癥指標水平，減輕患者體內炎癥狀態，間接為血清白蛋白合成創造良好環境。且葡萄糖酸鋅（Zinc Gluconate）這種類型的鋅補充劑胃腸道吸收較好，消化不良事件較少，是血液透析患者的潛在必要補充劑。

葡萄糖酸鋅（Zinc Gluconate）：血液透析患者的潛在必要補充劑

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Zinc Gluconate: A Potential Essential Supplement for Hemodialysis Patients

Hemodialysis patients face several problems, such as decreased serum albumin levels, poor sleep quality, and low quality of life. Due to increased excretion of serum albumin during hemodialysis, the serum albumin level in hemodialysis patients is usually lower than that in healthy individuals. In addition, the high - level inflammation and malnutrition in hemodialysis patients lead to a reduction in serum albumin synthesis.In terms of improving serum albumin levels, zinc is crucial for the albumin synthesis process. Studies have shown that zinc supplementation can enhance the activity of enzymes related to protein synthesis. In people with severe zinc deficiency, supplementation with Zinc Gluconate can significantly increase albumin levels. Meanwhile, in diabetic patients, zinc can reduce the loss of serum albumin, which brings hope for hemodialysis patients to increase their serum albumin levels. Moreover, the zinc status is closely related to the inflammatory response. Mild zinc deficiency can prompt monocytes to increase the production of pro - inflammatory markers such as interleukin 1 beta (IL - 1β), while zinc supplementation can regulate the inflammatory response, reduce the levels of inflammatory indicators such as C - reactive protein (CRP), alleviate the inflammatory state in patients, and indirectly create a favorable environment for serum albumin synthesis.

Zinc supplements in the form of Zinc Gluconate are well - absorbed by the gastrointestinal tract and are associated with fewer indigestion events, making them a potential essential supplement for hemodialysis patients.

Zinc Gluconate: A Potential Essential Supplement for Hemodialysis Patients

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